What are the effects of high levels of igf-1 in teens?

Growth. IGF-1 is one of the main "growth hormones" and is stimulated by pituitary growth hormone. During adolescence, the levels of IGF-1 are higher than at other times. A very high IGF-1 can occur due to acromegaly, which is a pituitary tumor making excess GH, but this is very rare. A pediatric endocrinologist is the expert on this.