6 doctors weighed in:

 is there a period of dopamine loss or disease process going on before symptoms occur?

6 doctors weighed in
Dr. Glen Elliott
Pediatrics - Psychiatry
4 doctors agree

In brief: Question unclear

Dopamine in the brain is associated with several disorders, most clearly parkinson's disease.
The question does not state what disorder is the topic of interest. Schizophrenia and adhd also are thought to involved Dopamine systems, but there is no evidence to suggest that either really are a direct result of Dopamine loss, just that medications may work through dopamine.

In brief: Question unclear

Dopamine in the brain is associated with several disorders, most clearly parkinson's disease.
The question does not state what disorder is the topic of interest. Schizophrenia and adhd also are thought to involved Dopamine systems, but there is no evidence to suggest that either really are a direct result of Dopamine loss, just that medications may work through dopamine.
Dr. Glen Elliott
Dr. Glen Elliott
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In brief: Parkinson's

I presume you are asking about parkinson's disease, which begins probably about 10-15 yrs prior to clinical signs.
It involves loss of Dopamine innervation of the basal ganglia, and especially affects pigmented cells within the pars compacta of the substania nigra. When cell loss exceeds 60%, the deficiency results in clinical motor symptoms.

In brief: Parkinson's

I presume you are asking about parkinson's disease, which begins probably about 10-15 yrs prior to clinical signs.
It involves loss of Dopamine innervation of the basal ganglia, and especially affects pigmented cells within the pars compacta of the substania nigra. When cell loss exceeds 60%, the deficiency results in clinical motor symptoms.
Dr. Bennett Machanic
Dr. Bennett Machanic
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Dr. Bennett Machanic
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