Why aren’t my medications for myasthenia gravis working?

May need change. Myasthenia medication responses vary from patient to pt, and there are several choices to treat. Steroids, mestinon, (pyridostigmine) ivig, even chemotherapies, may all play a role. However, sometimes, simple dosage adjustment may work. Also, look out for occult infections, or metabolic problems which may be sabotaging success.
Is it myasthenia? While you may well have a particularly difficult-to-treat case, it is important to confirm that you do indeed have myasthenia. If you have a positive antibody test, the diagnosis more assured. If not, a more extensive workup might be indicated. The most sensitive electrodiagnostic test for myasthenia is a single-fiber emg, which can be performed by a neuromuscular specialist.