Not known. There are neural tube defects related to low folate (folic acid) levels during pregnancy but cleft lip and palate is principally felt to be related to environmental toxins and/ or genetic inheritance. Folic acid deficiency is still being investigated as a possible cause.
May be. In experimental rats it has been shown that folate (folic acid) deficiency causes increased incidence of clefting of the face. Some people tried to extrapolate in human and feels giving extra Folic Acid during preganancy reduces the chance of having babies with cleft. But this has not been proven yet by clinical trial scientifically.
Often times. Taping or other devices are often used in babies with cleft lip (especially bilateral) to slowly bring the defect edges closer together and decrease the size of the gap that needs to be repaired.
Some do this. Some surgeons do taping prior to surgery, but most do not. There are other, more effective ways to bring the edges closer together prior to surgery if that is necessary.
My baby will have a Microarray analysis b/c he was born with a cleft lip/palate. Doc also noticed upslanting & epicanthal folds. Will test detect DS?
Yes. Your concern is Down's and this will be detected with a chromosomal analysis The condition is caused by an extra chromosome #21. Looking for this is now routine and will answer the question for you.
Cleft lip. I don't think so, but there is definitely some inhereted aspect of this deformity. Low income countries may not pay attention to the inheritance of this disease.
Yes. Yes it is and this has been related to nutritional deficiencies and prenatal care.
No. Genetics plays a strong role in the prevalence of clefting in many countries. Asian is highest rate, then caucasian is lower, and black african rate is the lowest. Of course folate (folic acid) deficiency contributes, but does not seem responsible for national rate differences.
What is the cause of unilateral cleft lip, submucus palate, tongue tie and bifid uvula in a female baby with first degree relatives parents?
Genetics & developme. Due to a factor of genetic contributions many feel that a cleft lip and palate may be associated with persistently high riding tongue in the oral cavity as well as failure of mesodermal penetration.
Unknown. All 4 conditions can occur individually or in various combinations. Causes for congenital deformities (birth defects) can include environmental factors (maternal nutritional deficiencies), inherited factors as well as spontaneous mutations. Although incest is not common or considered advisable for humans, I am not aware of a specific correlation with orofacial deformities.
Many factors. Cleft lip and palate can occur in many syndromes as well as in patients with no other abnormalities. The origin of these abnormalities is multifactorial. Family history is a strong indicator for genetic causes. Strong evidence shows that environmental factors such as b vitamin deficiencies in the mother during pregnancy play a role. A consult can help to identify specific factors and risks.