My sister is depressed and mean to me. This disease runs in the family, but I seem to set it off. Who can help.?

Talk to your. Parents... About your feelings... Family therapy can be very helpful and effective at helping family members get along better... Without any one person being blamed, or labeled... Even if you get them to take you to therapy just for yourself, that may be the first step, and then your therapist will help you recommend family therapy to your parents... Good luck!