3 doctors weighed in:

Leg muscles very sore since i started methotrexate 7.5 weekly is this a common side effect. 5mg of folate (folic acid) on days without mtx?

3 doctors weighed in
Dr. Vijay Karia
Internal Medicine
2 doctors agree

In brief: Methotrexate effects

Muscle soreness is not a common side effect, but can happen.
You should get further laboratory work up to check your liver, kidney and muscle enzymes. Yes, folate (folic acid) supplementation is recommended while taking methotrexate.

In brief: Methotrexate effects

Muscle soreness is not a common side effect, but can happen.
You should get further laboratory work up to check your liver, kidney and muscle enzymes. Yes, folate (folic acid) supplementation is recommended while taking methotrexate.
Dr. Vijay Karia
Dr. Vijay Karia
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