Can gallbladder disease cause liver tests to go up?

Yes. Liver function tests include ast, alt, alkaline phosphotase (alkp), and bilirubin.Acute inflammation of the gallbladder can secondarily inflame the liver, typically causing a elevation of ast and alt.A stone in the common bile duct (cbd) may block the liver and lead to abnormalities of all these labs. If a stone is in the cbd, endoscopic removal (ERCP) is usually necessary, in addition to chole-x.