2yo has for last 2 yrs high temps, seizures at end of temps, low protein globulin, no immunity to tetanus mumps diphtheria?

See details. There is, as you know, a potentially very serious issue. It may suggest significant compromise of the immune system related to such issues as hypogammaglobulinemia. Seek specialized pediatric evaluation such as with a pediatric immunologist. If there is a medical school reasonably close, consider seeking help there.