Is ventricular or atrial septal defect hereditary?

Most cases no. The chances of being born with a heart defect are approximately 8 per every thousand deliveries (a little under 1%). Most babies born with a heart defect (asd, vsd or any of a multitude of others) have no family members with heart disease. Now, when there is a first line family member with a heart defect the chances increase to about 2-3%, so there may be some genetic component.
Polygenic influence. The congenital heart defects are influenced by multiple genes on various separate chromosomes. Except for a few known to come up in specific autosomal dominant/recessive syndromes, most have minimal transmission risk.Inheritance of any chd from an affected parent is quoted at 4% for any chd (not necessarily the same one).If a parent with a chd has a child with a chd risk increases for the next pg.

Related Questions

Does atrial septal defect (asd) or ventricular septal defect (vsd) occur in some population groups more than others?

Yes. ASD is more common in females 2-3/1, while vsd is only slightly more common. A variety of heart defects are frequently seen in chromasome defects, trisomies, deletions etc. Some asian populations have a form of vsd at higher frequency. There are polygenic factors that increase risk within families with heart defects for offspring with a lesion. Read more...
Yes. Some types of chromosomal defects and some syndromes (not necessarily related to chromosome abnormalities) may have higher incidences of specific heart defects including asd's and vsd's. In general 8 out of every 1000 babies born will have a heart defect that will vary from the very simple to the very complex. Read more...

Is asd (atrial septal defect) hereditary?

Not completely. The genetic influence of congenital heart defects travels on several different genes & there is some risk for first degree relatives (offspring, sibs). The risk for offspring to have some heart defect (not the same) runs ~4% while it jumps to 6-8% if both parents have some form of defect. Of some interest, there is a basic 4% risk of some unexpected outcome for any pregnancy. (defect, premi, illness). Read more...
Yes, but complex. There is a hereditary component to atrial septal defects. Some patients with known genetic syndromes have ASDs as well. In most cases though, the mechanism of heritability is complex. Please discuss these issues with your physician to determine your specific risks. Read more...

Hello docs, is asd (atrial septal defect) hereditary?

In some cases. Some cases of atrial septal defect have a genetic component. An example is holt-oram syndrome which is caused by a mutation in the tbx5 gene. Tbx5 codes for a protein called t-box 5, which is a transcription factor active during fetal development and is important in the proper development of the heart and the upper extremities. Almost certainly, there are other important genes. Read more...

Is an atrial septal defect a hereditary condition?

Multiple genes . The information needed to code for normal formation of the heart travels in many genes. There is a linkage to other forms of congenital heard defect. Someone with an ASD will have a 4% risk of having a kid with some form of chd , not necessarily the same one. Read more...

Is asd (atrial septal defect) known as a hereditary condition?

Possibly. While there are some reports of familial clusters, generally it is a congenital condition affecting caused by a developmental defect. Read more...
There is. A higher likelihood of an ASD in a sibling or a child of a mom with add so yes, there is a genetic component. Read more...

Help please! Is asd (atrial septal defect) a hereditary condition?

Yes (in a sense) We are only just beginning to understand the genetics of congenital heart disease (chd). There are some specific genetic syndrome associated with asds. In addition, simply having an ASD does impart an increased risk--though small--of having children with chd. So yes, having chd is heritable, but in a multifactorial way (i.e. Not a single gene defect in many cases). Read more...

What does it mean to have atrial septal defect?

Atrial septal defect. An atrial septel defect is a hole or opening in the tissue that separates the left and right atrium. They are classified by location and named primum, secundum or patent foramen ovale. They can be observed or in some cases treated surgically to close them. Read more...

Is exercise dangerous for atrial septal defect]?

Cardiac exercises. No it shouldn't be if you speak to your cardiologist to find out what your limitations are. Read more...
Size matters. Small asds have little impact. Larger may, with exercize and increasing flow a person may have symptoms. Anymore , these are identified in youth and repaired so we do not see the natural history much anymore in the usa or developed world. Read more...
Likely Not. Exercise is beneficial for nearly everyone. The only exception may be if you have other conditions, pulmonary hypertension, or a history of blood clots. In general, exercise is a good thing. But again, please discuss your specific risks with your doctor before starting an exercise regimen. Read more...