4 doctors weighed in:

Is ventricular or atrial septal defect hereditary?

4 doctors weighed in
Dr. Robert Vogt Lowell
Pediatrics - Cardiology
2 doctors agree

In brief: Most cases no

The chances of being born with a heart defect are approximately 8 per every thousand deliveries (a little under 1%).
Most babies born with a heart defect (asd, vsd or any of a multitude of others) have no family members with heart disease. Now, when there is a first line family member with a heart defect the chances increase to about 2-3%, so there may be some genetic component.

In brief: Most cases no

The chances of being born with a heart defect are approximately 8 per every thousand deliveries (a little under 1%).
Most babies born with a heart defect (asd, vsd or any of a multitude of others) have no family members with heart disease. Now, when there is a first line family member with a heart defect the chances increase to about 2-3%, so there may be some genetic component.
Dr. Robert Vogt Lowell
Dr. Robert Vogt Lowell
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Dr. James Ferguson
Pediatrics
1 doctor agrees

In brief: Polygenic influence

The congenital heart defects are influenced by multiple genes on various separate chromosomes.
Except for a few known to come up in specific autosomal dominant/recessive syndromes, most have minimal transmission risk.Inheritance of any chd from an affected parent is quoted at 4% for any chd (not necessarily the same one).If a parent with a chd has a child with a chd risk increases for the next pg.

In brief: Polygenic influence

The congenital heart defects are influenced by multiple genes on various separate chromosomes.
Except for a few known to come up in specific autosomal dominant/recessive syndromes, most have minimal transmission risk.Inheritance of any chd from an affected parent is quoted at 4% for any chd (not necessarily the same one).If a parent with a chd has a child with a chd risk increases for the next pg.
Dr. James Ferguson
Dr. James Ferguson
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