My nana has had MS for about 20 years now and she keeps getting shingles this is her 3rd time! She cries because of the pain. Any treatment options?

Shingles. We now have a shingles vaccine, which can help prevent further episodes, and in this case, would strongly recommend. The pain can be managed with Lyrica (pregabalin). Unlikely that the shingles has any relationship to her MS, but would be wise for her to be taking a medication to stabilize the MS also.