13 doctors weighed in:
Is it safe to take Vyvanse and benadryl (diphenhydramine)?
13 doctors weighed in

Dr. Rudolf Brutoco
Pediatrics - Psychiatry
9 doctors agree
In brief: Safe but not advised
Benadryl (diphenhydramine) is too sedating, resulting often in some cognitive suppression.
The reason for taking the Vyvanse in the 1st place is to enhance cognition. There are better antihistamines. And, if the purpose of the Benadryl (diphenhydramine) is to help sleep at night, there are better choices.

In brief: Safe but not advised
Benadryl (diphenhydramine) is too sedating, resulting often in some cognitive suppression.
The reason for taking the Vyvanse in the 1st place is to enhance cognition. There are better antihistamines. And, if the purpose of the Benadryl (diphenhydramine) is to help sleep at night, there are better choices.
Dr. Rudolf Brutoco
Dr. Rudolf Brutoco
Thank
Dr. William Singer
Pediatrics - Neurology
1 doctor agrees
In brief: Conflicting
the sedating effect of benedryl may offset the stimulant effect of Vyvanse (lisdexamfetamine).
Be careful of driving and using machines until you are sure the benedryl is not sedating.

In brief: Conflicting
the sedating effect of benedryl may offset the stimulant effect of Vyvanse (lisdexamfetamine).
Be careful of driving and using machines until you are sure the benedryl is not sedating.
Dr. William Singer
Dr. William Singer
Thank
Dr. Alan Ali
Psychiatry
1 doctor agrees
In brief: Vyvanse/benadryl
should be ok.

In brief: Vyvanse/benadryl
should be ok.
Dr. Alan Ali
Dr. Alan Ali
Thank
Dr. Allen Seely
General Practice
In brief: OK Benedryl+Vyvanse
Benedryl is an 'sedating' antihistamine and is safe with Vyvanse (lisdexamfetamine) (add med) benedryl is best dosed @ night.

In brief: OK Benedryl+Vyvanse
Benedryl is an 'sedating' antihistamine and is safe with Vyvanse (lisdexamfetamine) (add med) benedryl is best dosed @ night.
Dr. Allen Seely
Dr. Allen Seely
Thank
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