Is there anything I can do about acute abdominal pain in the belly button region?

Find the cause. What to do about pain around the belly button will depend on what the cause is. There are many organs in the region and causes of the pain can range from trivial skin issues to urgent surgical emergencies such as acute appendicitis. Since there is no way to figure that out at home, you need to seek medical care to sort through it. Do not delay. Good luck.