What is the chance of having another child with a neural tube defect?

8x greater risk. It has been shown that having a child with a neural tube defect increases the chance of having a second child with a similar defect. The recurrence risk in this situation is 8 times greater than the risk if no such history was present. Also if there is any family history of neural tube defects there is an increased risk of an affected pregnancy even if not immediate relative (2cd or 3d degree).

Related Questions

Which is the chance of having more then one child with a neural tube defect?

NT defect. This depends on the cause of the defect, but overall, your risk for a second child with a neural defect increases after you have a child with a defect. Your OB will likely suggest taking a higher dose of folic acid when you are thinking of conceiving. Read more...

What kind of likelihood is there of having more then one child with a neural tube defect?

It varies. If parents have had one child with a neural tube defect their risk of having another child with a defect is about 3 %. If they have had two children with the defect their risk increases to about 7 %. A parent who has a neural tube defect also has about a 3 % risk of having a child with a neural tube defect. All of these risks can be lowered significantly by maternal Folic Acid ingestion. Read more...
NT Recurrence rate. If you have one child with a neural tube defect, chances are higher that a second child will have one are 10-30x's that of the general population, between 1 in 40 and 1 in 100 depending on type of defect. Read more...

How do you know if your baby has a neural tube defect before birth?

MSAFP and ultrasound. Maternal serum Alpha fetoprotein at 16 weeks and detailed ultrasound at 18-20 weeks should detect fetal open neural tube defects with 96% accuracy. Closed neural tube defects are more difficult to diagnose but are more innocuous too. Read more...

Is a neural tube defect a chromosomal mutation or a gene mutation?

Both or neither. While neural tube disorders can be a genetic mutation (gene is a functional unit of heredity occupying a specific spot--locus--on a chromosome), they occur most commonly in the setting of Folic Acid deficiency during pregnancy--hence prenatal vitamins with folic acid. Ntds occur in 1/1000 births, and range from spina bifida occulta to anencephaly. Read more...

Is it true that a neural tube defect is a chromosomal mutation or a gene mutation?

Yes and more. Neural tube defects can be brought on by genetics, nutrition, and environmental factors. Women who are deficient in Folic Acid before or during pregnancy are at a higher risk for neural tube defects. Women who are obese, have poorly controlled diabetes, or take medication such as Dilantin, Tegretol, or Depakote are at higher risk for neural tube defects or anencephaly. I hope this helps. Take c. Read more...