3 doctors weighed in:
What biological sex is determined in klinefelters syndrome?
3 doctors weighed in

Dr. Thomas Namey
Internal Medicine - Rheumatology
1 doctor agrees
In brief: Male.
Klinefelter's syndrome is a male xx/y individual.
In otherwords, an y-chromosomal male with two female chromosomes. Other than having after puberty very high estrogen levels and lower than normal testosterone, they actually have the highest incidence of connective tissue diseases in the lupus family, but the percentage still is not high!

In brief: Male.
Klinefelter's syndrome is a male xx/y individual.
In otherwords, an y-chromosomal male with two female chromosomes. Other than having after puberty very high estrogen levels and lower than normal testosterone, they actually have the highest incidence of connective tissue diseases in the lupus family, but the percentage still is not high!
Dr. Thomas Namey
Dr. Thomas Namey
Thank
1 comment
Dr. George Klauber
Agree with Dr. Namey's answer except that subjects with Klinefelters have an extra X chromosome , thus are usually XX/Y, more rawly have 48 chromosomes/nucleus i.e XX/YY or XXX/Y
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