3 doctors weighed in:

How is a retinoblastoma caused?

3 doctors weighed in
Dr. Andrew Turrisi
Radiation Oncology
2 doctors agree

In brief: Chromosme 13

Has a paired site where the rb gene lives.
It can be inherited, or occur accidentally (sporadic) mutation. The rb gene loss leads to the eye tumor, but it is also is involved with other tumors, and its chromosomal location is close to a region associated with bone tumors.

In brief: Chromosme 13

Has a paired site where the rb gene lives.
It can be inherited, or occur accidentally (sporadic) mutation. The rb gene loss leads to the eye tumor, but it is also is involved with other tumors, and its chromosomal location is close to a region associated with bone tumors.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
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