What is periventricular leukomalacia?

PVL is caused by. Lack of blood flow & oxygen to the white matter around the ventricles of the brain, an area most susceptible to damage around the end of the 2nd trimester. Severity of impairment varies widely, but isn't seen right away. Start Early Intervention therapy at 4-6 weeks as "Early Prevention" for optimal outcome. See: http://cerebralpalsy. Org/about-cerebral-palsy/cause/periventricular-leukomalacia/
White matter disease. Surrounding the fluid spaces within the brain are white (myelinated) nerve fiber tracts. These are susceptible to damage, usually due to small vessel circulatory problems. Other causes: hypertension, low blood sodium, brain trauma, genetics, low blood oxygen levels, alcoholism, certain drugs.

Related Questions

What's periventricular leukomalacia?

Periventricular Leuk. Premature infant is prone to cerebral hemorrhage. Infarction of the periventricular white matter is called periventricular leukomalacia.
PVL is caused by. Lack of blood flow & oxygen to the white matter around the ventricles of the brain, an area most susceptible to damage around the end of the 2nd trimester. Severity of impairment varies widely, but isn't seen right away. Start Early Intervention therapy at 4-6 weeks as "Early Prevention" for optimal outcome. See: http://cerebralpalsy. Org/about-cerebral-palsy/cause/periventricular-leukomalacia/

What's the prognosis for periventricular leukomalacia (pvl) in a baby?

See below. The prognosis varies. It depends on the severity of the pvl, and any other problems. The child should have his/her development followed closely. They may benefit from early intervention services, as well.
White matter of. The brain around the ventricles is very susceptible to damage from drops in oxygen or blood flow, especially near the end of the 2nd trimester. Thus, it can occur in a fetus or in a VLBW "preemie". Though diagnosed by cranial ultrasound, the degree of damage visible on MRI of the brain at discharge from the NICU is the best predictor of risk for developmental delays & motor impairment.

What are the tests for periventricular leukomalacia?

Visible on US or CT. An ultrasound done through the soft spot will often detect pvl. Ct or MRI might also be helpful but the cranial ultrasound is easy to do & requires little preparation or stress on the patient so it is the more common study for this dx.
PVL is caused by. Lack of blood flow & oxygen to white matter around the ventricles of the fetal brain, an area most susceptible to damage around the end of the 2nd trimester. Cranial ultrasounds are done on newborns with risk factors by history or neurologic abnormalities by exam. An MRI of the brain is also diagnostic. Symptoms vary widely & may not be obvious early on, but Early Intervention is important.

What are the symptoms of periventricular leukomalacia?

Symptoms. Periventricular leukomalacia is a condition that mostly affects preterm infants. The hallmark symptom present in these children is a bilateral spasticity of the lower limbs.

What is the treatment for periventricular leukomalacia?

Supportive care. The term periventricular (next to the ventricles) leukomalacia (white matter looking soft) is an observation. It suggests a previous injury to the area that is showing up by a change in the white mater. Treatment is supportive;maintaining nutrition, ventilation & fluids.
Dr. F. discussed. Acute care. At the time of discharge from the NICu, an MRI of the brain is most predictive of outcome. The NICU will give you contact info for your state's Early Intervention Program. Enroll your baby & start services right away, even though you probably won't see any signs of motor impairment, as Occupational & Physical Therapy can minimize development of abnormal motor patterns.

What is the definition or description of: Periventricular leukomalacia?

PVL. Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of the disorder.

I am a basket case. My son has periventricular leukomalacia. Can you tell me something about it?

Discriptive term. Pvl is used to describe changes in the appearance of the brain substance that is adjacent to the ventricles of the brain (spinal fluid containing sacs in the middle). This occurs when blood flow or oxygen delivery to those sites was interupted and injury occured. Outcome is variable & movement disorders& motor delay are common. Therapy will often improve outcome. Developmental followup is a must.
Disabilites. Unfortunately, periventricular leukomalacia, or pvl usually occurs in pre-term infants, but can occur in-utero when there has been placental insufficiency causing poor perfusion to the fetal brain. They are cysts that form when those areas of the brain essentially die. They are around the ventricular system of the brain, where the neurons involved regulate movement. Cerebral palsy is usually seen.
Hope this helps. You didn't indicate if he is a preemie, had any other neurological problems, nor his age, so I can't address his specific prognosis. I can only tell you that I've had patients whose MRI findings looked a lot worse than they did and that early intervention really will help both of you. You deserve a safe place to vent your feelings so you can focus on learning what you can do to help your son.

Would like to know what immediate action can be taken for a child (11 yrs) suffering from "periventricular leukomalacia" has an attack of fits.?

Loss of blood flow & oxygen causes death of white matter around the fluid-filled ventricles of the fetal brain, often between 26-42 wks. More common in "preemies", some causes are infection, maternal cocaine or meth use & bleeding in the ventricles. Pediatric neurologists treat Spastic Cerebral Palsy & Seizures. Special Education is needed for Intellectual Disability or Specific Learning Disability. See below.

Are there good alternative medicines for kids with periventricular leukomalacia?

No. Periventricular leukomalacia is a condition where brain tissue has been lost in so-called "water-shed" areas. Since the tissue is gone, there is no treatment per se, although one may need to treat associated disorders, such as muscle stiffness or dysfunction, with medical or non-medical therapies.
No. The researchers and doctors are trying to find effective treatment and preventive methods for pvl, but unlucky so far. The one suggestion only: don't have preterm delivery and don't use Cocaine during the pregnancy.