8 doctors weighed in:
How do brain lesions diagnose multiple sclerosis, Lewy body dementia, etc?
8 doctors weighed in

4 doctors agree
In brief: LBD Clinical only
Neurodegenerative, progressive d/o with  milder physical parkinsonism than parkinson's disease typically.
(slowed movements, stiff/rigid muscles & posture, possibly resting tremor). But with early dementia, often with associated psychosis (visual hallucinations/delusional thoughts, excessive sleepiness, depression, anxiety, apathy, & rbd=rem behavior d/o, causing acting-out of dreams in rem sleep.

In brief: LBD Clinical only
Neurodegenerative, progressive d/o with  milder physical parkinsonism than parkinson's disease typically.
(slowed movements, stiff/rigid muscles & posture, possibly resting tremor). But with early dementia, often with associated psychosis (visual hallucinations/delusional thoughts, excessive sleepiness, depression, anxiety, apathy, & rbd=rem behavior d/o, causing acting-out of dreams in rem sleep.
Dr. Robert Hutchman
Dr. Robert Hutchman
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Dr. James Shackson
Psychiatry
2 doctors agree
In brief: Diagnosis/symptoms
Brain lesions are the actual physical changes in the structure of the brain or individual cells of the brain that account for the psychiatric symptoms we may see, for example tangles and plaques in alzheimer's disease that cause clinical symptoms like memory loss or mood/personality changes.
Some brain lesions are found on imaging, like a ct or MRI scan, while others requires microscopic exam.

In brief: Diagnosis/symptoms
Brain lesions are the actual physical changes in the structure of the brain or individual cells of the brain that account for the psychiatric symptoms we may see, for example tangles and plaques in alzheimer's disease that cause clinical symptoms like memory loss or mood/personality changes.
Some brain lesions are found on imaging, like a ct or MRI scan, while others requires microscopic exam.
Dr. James Shackson
Dr. James Shackson
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Dr. Susan Uhrich
Psychiatry
1 doctor agrees
In brief: It's what makes
Up the lesions that tell us what we are dealing with.

In brief: It's what makes
Up the lesions that tell us what we are dealing with.
Dr. Susan Uhrich
Dr. Susan Uhrich
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In brief: Use of MRI testing
The brain lesions in MS are seen within white matter in particular patterns, and different lesion ages can confirm MS.
Lewy body dementia is more difficult to diagnose looking for specific lesions and PET scan with decreased occipital lobe metabolism can confirm. Likewise, PET can show specific patterns for fronto-temporal and Alzheimer's dementias.

In brief: Use of MRI testing
The brain lesions in MS are seen within white matter in particular patterns, and different lesion ages can confirm MS.
Lewy body dementia is more difficult to diagnose looking for specific lesions and PET scan with decreased occipital lobe metabolism can confirm. Likewise, PET can show specific patterns for fronto-temporal and Alzheimer's dementias.
Dr. Bennett Machanic
Dr. Bennett Machanic
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