13500 WBC 46% lymps, chronic muscle deep tissue infection, pain in knees. Responded using ciprofloxicin to tr ear infection. Blood culture next?

Knee infection . The best way to rule out knee joint infection is to aspirate the knee joint and examine the fluid for organisms and perform cell count and culture/sensitivity to determine appropriate antibiotics. If you have high fever and chills consistent with generalized illness then blood culture will be necessary. You need to see you doctor who can examine you and decide what to do next good luck.