can result from chronic irritation from condyloma
acuminata, perianal fissures/fistulae, chronic hemmorrhids, leukoplakia
, and trauma from anal intercourse.
This presents with a triad of bleeding, pain, and perianal mass. Anal fissures, by themselves, do not lead to cancer, but if they are caused by some chronic process (anal intercourse), the epithelium react and can become cancer.