13 doctors weighed in:

What are the best treatments for late stage lung cancer based on pathology type?

13 doctors weighed in
Dr. Liawaty Ho
Internal Medicine - Hematology & Oncology
4 doctors agree

In brief: Chemotherapy

Chemotherapy plus minus biological agent will be the treatment in advance stage lung cancer.
The type of treatment will depend on the pathology (small cell vs non small cells ( adeno, squamous, large cells etc) , and other more sophisticated biomarkers/ genetic analysis profile- ie. Egfr mutation status, alk-1, etc. See your oncologist and discuss further regarding treatment option in detail.

In brief: Chemotherapy

Chemotherapy plus minus biological agent will be the treatment in advance stage lung cancer.
The type of treatment will depend on the pathology (small cell vs non small cells ( adeno, squamous, large cells etc) , and other more sophisticated biomarkers/ genetic analysis profile- ie. Egfr mutation status, alk-1, etc. See your oncologist and discuss further regarding treatment option in detail.
Dr. Liawaty Ho
Dr. Liawaty Ho
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1 comment
Dr. Ed Kaplan
Newer biologic therapies, such as erlotonib (Tarceva) with or without bevacizumab (Avastin) can sometimes be effective even without the use of chemotherapy. Other biologic treatments available (i.e.: crizotinib for alk-posivie tumors) or soon to be available can be very effective.
Dr. ALADIN MARIANO
Surgery - Thoracic
3 doctors agree

In brief: Chemotherapy

Whatever the type of malignancy, late stage, i.
e. Stage iv, suggests the tumor has gone beyond local control and cannot be treated effectively except with chemotherapy, commonly platinum-based. However, this does not preclude surgery or radiorx which may limit "tumor-burden" and relieve some symptoms. Chemotherapy is ideal for small-cell carcinoma.

In brief: Chemotherapy

Whatever the type of malignancy, late stage, i.
e. Stage iv, suggests the tumor has gone beyond local control and cannot be treated effectively except with chemotherapy, commonly platinum-based. However, this does not preclude surgery or radiorx which may limit "tumor-burden" and relieve some symptoms. Chemotherapy is ideal for small-cell carcinoma.
Dr. ALADIN MARIANO
Dr. ALADIN MARIANO
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Dr. Isaac Blum
Internal Medicine
3 doctors agree

In brief: Chemotherapy

To late for surgery alone.

In brief: Chemotherapy

To late for surgery alone.
Dr. Isaac Blum
Dr. Isaac Blum
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2 comments
Dr. Ed Kaplan
Newer biologic therapies, such as erlotonib (Tarceva) with or without bevacizumab (Avastin) can sometimes be effective even without the use of chemotherapy. Other biologic treatments available (i.e.: crizotinib for alk-positive tumors) or soon to be available can be very effective.
Dr. Eric Toloza
but chemo for non-small cell lung cancer differs somewhat from that for small cell lung cancer
Dr. Ed Friedlander
Pathology
1 doctor agrees

In brief: Variable

If i had recurrent small cell carcinoma that had become refractory to chemotherapy, i would thank my caregivers and go to hospice; pain-management / comfort-measures only.
If i had one of the "never-smoker" cancers likely to respond to the new agents, i'd try "iressa" or something similar. For non-small-cell, i would ask my would-be oncologist some hard questions and make an informed choice.

In brief: Variable

If i had recurrent small cell carcinoma that had become refractory to chemotherapy, i would thank my caregivers and go to hospice; pain-management / comfort-measures only.
If i had one of the "never-smoker" cancers likely to respond to the new agents, i'd try "iressa" or something similar. For non-small-cell, i would ask my would-be oncologist some hard questions and make an informed choice.
Dr. Ed Friedlander
Dr. Ed Friedlander
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