Have had anal itch for few years...Have seen dr.'s and prescribed pramasone which helps for a time but comes back...Scratch a lot while sleep. Advice?

There are many . Potential causes for anal itching. I recommend that you see a dermatologist for as second opinion. www.mayoclinic.org/.../anal-itching/.../causes/con-20023539 anal itching — comprehensive overview covers causes, treatment of this common, sometimes embarrassing condition. Good luck and best wishes.