Could the hpa axis be stimulated?

Life does it for you. Please forgive my frankness. "Hypothalamic pituitary adrenal axis disorder" is a fad diagnosis, not generally accepted, but with just enough science to be interesting. Some folks who are troubled by the blahs have nonspecific abnormalities on testing. This is best managed by fitness, looking at attitudes, beliefs, life situations and living skills -- the mind helps cure the body. Best wishes.