Infection and pain. This is a relatively safe procedure but the marrow is harvested by taking a small amount from your hip bone. You lie on your stomach, the skin' muscle overlying the hip bone is anesthetized and cleaned. A needle is then inserted into the bone and gently rotated until it is deep enough to get to the marrow. A small amount is drawn out and the needle is removed. It is an outpatient procedure.
Soe risk? But many. We want to assure donor safety, but no medical procedure is risk-free. The majority (more than 98.5%) of donors from the be the match registry feel completely recovered within a few weeks. A small percentage (1.34%) of donors experience a serious complication due to anesthesia or damage to bone, nerve or muscle in their hip region. The risk of side effects of anesthesia is well known.
Life saving. Benefit is not dying from the disease being treated with transplant. Risks are death from infection, or organ damage from treatment. Later on, risk is graft vs host disease (gvhd) where the new immune system attacks the recipient. Common sites are skin, mucus membranes, GI tract, liver. Infection also more likely with gvhd. Drugs can damage joints, esp. Hips and shoulders. Varies how severe.
There are many. The exact risks are dependent on the type of transplant chemotherapy or radiation given, who the donor is (self or somebody else) as well as how close the match is. There are some life threatening complications. There is a high infection risk, effects on the immune system and need for blood transfusions. Nausea, vomiting and fatigue are very common too.