Yes! Cystic fibrosis is associated with male infertility, since men who carry the gene for CF may have blockage in the sperm collecting tubes. Azospermia, no sperm, is a common result. Sperm can be retrieved with a small needle and used for in vitro fertilization (ivf), using icsi. Diagnostic tests are available to reduce the risk of having a child affected with cf.
Assisted fertility. Almost all men with CF have absent vas deferens, this is part & parcel of the condition. He may well be a candidate for ivf by icsi (intracytoplasmic sperm injection). This would involve a fertility expert. However, it would be advisable for him & any partner to consult with a geneticist because this is an inherited condition.