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What is the difference between major depression with melancholia and major depression?

4 doctors weighed in
Dr. Neil Liebowitz
Psychiatry
3 doctors agree

In brief: A subtype

Melancholia is a subtype of depresson which generally is more severe with lack of reactivity in mood.
There are more physical symptoms of no drive, motivation, apathy but can have a dramatic change from am to pm with much worse mood in the am. Melancolic depression is less responsive to therapy alone and often requires multiple medications or ect.

In brief: A subtype

Melancholia is a subtype of depresson which generally is more severe with lack of reactivity in mood.
There are more physical symptoms of no drive, motivation, apathy but can have a dramatic change from am to pm with much worse mood in the am. Melancolic depression is less responsive to therapy alone and often requires multiple medications or ect.
Dr. Neil Liebowitz
Dr. Neil Liebowitz
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