Related Questions

My mom, Safia, 60 years old, resident of Pakistan has drug induced parkinsonism, which is bothering a lot & worsening. Sinemet (carbidopa and levodopa) 25/250 every 4.5 hours?

Tachyphylaxis. Dosing of Sinemet (carbidopa and levodopa) is a little strange, requiring front loading in the day and a long gap at night without dosing. If taken like most other medications, on a more regular dosing interval, tachyphylaxis develops, which essentially means the efficacy of the medication reduces. Read more...