3 doctors weighed in:

Please explain what are the differences between glyburide and glimepiride medications?

3 doctors weighed in
Dr. Thomas Knecht
Internal Medicine - Endocrinology
2 doctors agree

In brief: Similar mechanisms

Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release.
They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap.

In brief: Similar mechanisms

Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release.
They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap.
Dr. Thomas Knecht
Dr. Thomas Knecht
Thank
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