Not usually. It is important to let your dentist know, but most procedures don't have a major impact for sickle cell. Procedures that involve more bleeding would be of greater concern, things like extractions, dental implants, etc.
Not realy. Since these new guidelines came out last year, our sickle cell center no longer routinely recommends antibiotics for dental work for sickle cell patients -- only for selected situations local anesthesia rather than conscious sedation or general anesthesia. All of these concerns are greater for children with hemoglobin ss and hemoglobin s-beta-zero thalassemia, than for those with other types types.