4 doctors weighed in:

What is the etiology of ewing sarcoma?

4 doctors weighed in
Dr. Ahmad M Hadied
Orthopedic Surgery
2 doctors agree

In brief: No body know

For sure what the etiology a lot research are going on.

In brief: No body know

For sure what the etiology a lot research are going on.
Dr. Ahmad M Hadied
Dr. Ahmad M Hadied
Thank
1 comment
Dr. Noah Federman
The underlying molecular defect in Ewing sarcoma is a translocation of two genes creating a fusion product. The most common product is EWS-FLI1. This is present in about 90% of Ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of Ewing sarcoma.
Dr. Noah Federman
Pediatrics - Hematology & Oncology

In brief: Etiology ewings

The underlying molecular defect in ewing sarcoma is a translocation of two genes creating a fusion product.
The most common product is ews-fli1. This is present in about 90% of ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of ewing sarcoma.

In brief: Etiology ewings

The underlying molecular defect in ewing sarcoma is a translocation of two genes creating a fusion product.
The most common product is ews-fli1. This is present in about 90% of ewing sarcomas. The fusion protein is believed to be the inciting cancer event believed play a role in abnormal transcription, translation and the overall malignant phenotype of ewing sarcoma.
Dr. Noah Federman
Dr. Noah Federman
Thank
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