5 doctors weighed in:
Does hemophilia only affect men?
5 doctors weighed in

Holly Barth
General Practice
2 doctors agree
In brief: It is more likely
Hemophilia mostly affects men.
It is rare but not impossible for a female to have hemophilia. Hemophilia is a sex-linked recessive disorder: the trait is carried on the x chromosome which a female has two of and a male only has one. This means a female would have to inherit two copies of the hemophilia gene to have the disorder. A male only has to inherit one copy.

In brief: It is more likely
Hemophilia mostly affects men.
It is rare but not impossible for a female to have hemophilia. Hemophilia is a sex-linked recessive disorder: the trait is carried on the x chromosome which a female has two of and a male only has one. This means a female would have to inherit two copies of the hemophilia gene to have the disorder. A male only has to inherit one copy.
Holly Barth
Holly Barth
Answer assisted by Holly Barth, Medical Student
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Dr. Scott Diede
Pediatrics - Hematology & Oncology
1 doctor agrees
In brief: No.
As previously mentioned, a homozygous female would be symptomatic.
However, 10% of women who are carriers can also be symptomatic because of a phenomenon known as x-chromosome inactivation. Factor levels in these people can be reduced low enough that they have symptoms (though not as bad a severely affected males).

In brief: No.
As previously mentioned, a homozygous female would be symptomatic.
However, 10% of women who are carriers can also be symptomatic because of a phenomenon known as x-chromosome inactivation. Factor levels in these people can be reduced low enough that they have symptoms (though not as bad a severely affected males).
Dr. Scott Diede
Dr. Scott Diede
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