1 doctor weighed in:

Is Accutane or bactrim (sulfamethoxazole and trimethoprim) better for acne, what to do?

1 doctor weighed in
Dr. Ed Friedlander
Pathology

In brief: How bad is it?

Isotretinoin is the strongest and most effective medication for acne and is not for the faint-hearted.
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic and should never be used as sole therapy; a combination of topical benzoyl peroxide plus a course of systemic tetracycline often clears moderately severe acne. If you're female, the oral contraceptive pill if right for you may work; spironolactone's another rx.

In brief: How bad is it?

Isotretinoin is the strongest and most effective medication for acne and is not for the faint-hearted.
Bactrim (sulfamethoxazole and trimethoprim) is an antibiotic and should never be used as sole therapy; a combination of topical benzoyl peroxide plus a course of systemic tetracycline often clears moderately severe acne. If you're female, the oral contraceptive pill if right for you may work; spironolactone's another rx.
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