Is there treatment for systemic sclerosis?

Not really. D-penicillamine might work, and there a number of studies suggesting this, but no long term double blind studies exist. A recent report suugest that a drug CellCept (mycophenolate mofetil) might be of value, and there are those that use mtx or tetracyclines.The major advances are ability to control BP and treat pulmonary hypertension. We can deal with esophgeal spasm and reflux. Nothing great at present for underlying dx.

Related Questions

Will systemic sclerosis kill me if I don't get treatment? Is it just a slow disease?

Yes. Systemic sclerosis is a slow progressive but relentless disease. Current treatments are of limited efficacy. Having said that, you should follow closely with a rheumatologist. Read more...

What are the tests for systemic sclerosis?

Biopsy, blood. In advanced stages, no test is required. It if the diagnosis is suspected early, a skin biopsy will usually prove the diagnosis. In the blood, the scl-70 and the anti-centromere antibody tests are the most helpful. Other tests may be positive. The above two blood tests often help differentiate the disease from other conditions. Other tests are used to evaluate but not diagnose the condition. Read more...

My father was diagnosed with systemic sclerosis. Should I be worried for him?

Timely help is key. Systemic sclerosis remains a challenging disease in the field of rheumatology where struggle for a cure or even targeted therapy is ongoing. Most patients donot have adverse outcome but in case of lung and kidney involvement prognosis can be poor. There are many other areas of the body affected by it but they don't seem to be dangerous rather patient lifestyle and medication can help. Read more...
Not necessarily. Although genetic factors may play a role in scleroderma it does not necessarily run in families. It is a memebre of the connective tissue family. Other causes such as viruses ahve been suggested and other environment exposures such as chemical solvents and there is a vinyl chloride scleroderma like syndrome. The etology is not known and thus your father's scleroderma may not . Read more...

Do you ever diagnose systemic sclerosis sine scleroderma and if so, what are the the clinical signs and symptoms of this disease?

Internal . Systemic sclerosis sine scleroderma would have some positive autoantibodies such as ANA on lab work and may involve only internal areas such as the esophagus or lungs. Difficulty with swallowing may be seen. See a rheumatologist for a full work up, evaluation and treatment. Read more...
Extremely rare. Systemic sclerosis sine scleroderma is a fibrosing condition of the internal organs including the GI tract, pulmonary artery, and lungs, but lacking the skin features if scleroderma. Systemic sclerosis is a rare condition to begin with, and systemic sclerosis sine scleroderma accounts for <10% of patients. Diagnosis might include antibody tests or abnormal biopsy of affected internal tissues. Read more...

What is systemic sclerosis?

Systemic sclerosis. An autoimmune disease characterized by thickening and loss of elasticity of the skin. It may have systemic manifestations as well such as trouble swallowing and acid reflux. Read more...

What were your initial symptoms of systemic sclerosis?

Raynaud's . Raynaud's 1st but other systems can be involved - skin tightening, each person is different and on occasion the skin can be normal. Read more...

What is the definition or description of: Systemic sclerosis?

Systemic sclerosis. This is based on several criteria and includes skin thickening; Raynaud's phenomenon; abnormal lab studies (anti-Scl 70); abnormal nail capillaries; and in some case lung disease. For more detail, be sure to consult a rheumatologist. Read more...