How long does it take to get rid of histoplasmosis?

Histoplasmosis. For asymptomatic people or people with acute localized infection who are otherwise healthy, antifungal treatment is usually not recommended as these people have or will resolve the infection in about three weeks. If symptoms persist a month or more, itraconazole (sporanox), ketoconazole (nizoral) or Amphotericin B (fungizone, amphocin) may be effective.