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How does smoking affect arterial blood gas results?
1 doctor weighed in

Dr. Stephen Siegel
Internal Medicine - Pulmonology
In brief: Measure CO level
An arterial blood gas measures the blood pH (normal 7.
40), po2 (partial pressure of oxygen), pco2, partial pressure of co2 and the bicarbonate (sodium bicarbonate) level is calculated. Smoking increases carboxyhemoglobin level with carbon monoxide binding to the hemoglobin displacing oxygen. The po2 is unaffected by carbon monoxide but the hemoglobin delivers carbon monoxide (a poison) to tissues instead of oxygen.

In brief: Measure CO level
An arterial blood gas measures the blood pH (normal 7.
40), po2 (partial pressure of oxygen), pco2, partial pressure of co2 and the bicarbonate (sodium bicarbonate) level is calculated. Smoking increases carboxyhemoglobin level with carbon monoxide binding to the hemoglobin displacing oxygen. The po2 is unaffected by carbon monoxide but the hemoglobin delivers carbon monoxide (a poison) to tissues instead of oxygen.
Dr. Stephen Siegel
Dr. Stephen Siegel
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