8 doctors weighed in:
What mutations cause fetal alcohol syndrome facial features in a baby or child, whose mother was a non-drinker?
8 doctors weighed in

Dr. Joseph Eastern
Dermatology
5 doctors agree
In brief: First of all...
...Alcoholics frequently deny that they drink; so if there are features suggesting fas, you have to be sure the mother really is a non-drinker. That said, cornelia de lange syndrome, velocardiofacial syndrome (vcfs), & dubowitz syndrome - & probably others - share features with fas, though they are rarer. A precise diagnosis requires a thorough exam and lab testing by an expert in this field.

In brief: First of all...
...Alcoholics frequently deny that they drink; so if there are features suggesting fas, you have to be sure the mother really is a non-drinker. That said, cornelia de lange syndrome, velocardiofacial syndrome (vcfs), & dubowitz syndrome - & probably others - share features with fas, though they are rarer. A precise diagnosis requires a thorough exam and lab testing by an expert in this field.
Dr. Joseph Eastern
Dr. Joseph Eastern
Thank
Dr. Michael Fisher
Dermatology
1 doctor agrees
In brief: Fetal alcohol
The deleterious effects of ethanol on the developing human brain are poorly understood.
Here it is reported that ethanol, acting by a dual mechanism [blockade ofn-methyl-d-aspartate (nmda) glutamate receptors and excessive activation of gabaa receptors], triggers widespread apoptotic neurodegeneration in the developing rat forebrain. Vulnerability coincides with the period synaptogenesis.

In brief: Fetal alcohol
The deleterious effects of ethanol on the developing human brain are poorly understood.
Here it is reported that ethanol, acting by a dual mechanism [blockade ofn-methyl-d-aspartate (nmda) glutamate receptors and excessive activation of gabaa receptors], triggers widespread apoptotic neurodegeneration in the developing rat forebrain. Vulnerability coincides with the period synaptogenesis.
Dr. Michael Fisher
Dr. Michael Fisher
Thank
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