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Can macrocytic anemia be due to colon cancer? Mcv 103 and hemoglobin 9.8 for old male. I know only microcytic anemia aan be due to colon cancer?

1 doctor weighed in
Dr. Sewa Legha
Internal Medicine - Oncology

In brief: Yes it depends

You are right that anemia from blood loss like from colon cancer is typically microcytic with a low MCV but the MCV in your case is not high enough to suspect a typical macrocytic anemia like one due to B12 deficiency.
Yet we can have a mixed picture. At the moment we are only guessing all this till you have the right investigating/testing done. So i would check your B12 level and bone marrow exam.

In brief: Yes it depends

You are right that anemia from blood loss like from colon cancer is typically microcytic with a low MCV but the MCV in your case is not high enough to suspect a typical macrocytic anemia like one due to B12 deficiency.
Yet we can have a mixed picture. At the moment we are only guessing all this till you have the right investigating/testing done. So i would check your B12 level and bone marrow exam.
Dr. Sewa Legha
Dr. Sewa Legha
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