Is there post-exposure prophylaxis for multi-resistant organisms such as mrsa, vre, esbls, mbls?

Not really. For MRSA there is therapy to try and change your nasal and skin carriage states. For gut flora the use of unpasteurized yogurt or probiotics may reduce the relative numbers of unwanted bacteria, but there are no recommendations for antibiotic prophylaxis and this should be strongly discouraged as it is likely to worsen things.