I have had sinus drainage several days now I have been taking Benadryl (diphenhydramine) and zyrtec and a chough med very little help what should I do?

Saline nose spray. Musinex, cool mist vaporizer if yellow or green drainage see your doctor if not better after a total of 7-10days.
There. Is a right time for antibiotics, talk to your doctor, antihistamines sometimes are not enough.