On day 6 of Zoloft (sertraline) and feel tired and kind of sick. I usually exercise a lot but have not been this week. Could it help if I start back exercising?

Zoloft (sertraline) Zoloft (sertraline) can cause side effects of tiredness and nausea, at least temporarily. Hopefully they will pass within a couple of weeks. If exercising in general helps you feel better, it may work this way at this time also.