Different strain. Hiv-1 and hiv-2 both produce aids, both are lethal if untreated, infection spread same way. Hiv- 2 is less common mostly confined to west africa, genetic test will differentiate one from other.
Different types. HIV-1 and HIV-2 are different types of HIV. Both HIV-1 and HIV-2 can usually be detected through the usual HIV-1/2 antibody test. However, HIV-2 is more than 55% genetically different from HIV-1. Due to this genetic difference, HIV-1 and HIV-2 antigens are distinct enough that if a test is developed only to detect HIV-1, it will not reliably detect HIV-2.
Source of infection. Hiv-1 is the more common form of HIV in the usa/europe, while hiv-2 occurs predominantly in west african nations, and former portuguese colonies, such as angola, mozambique, and brazil, and in parts of india (goa, maharashtra). Many hiv1 medications are effective against hiv2. Usa cases of hiv2 are projected to be several hundred, although estimates vary.
Antigenicity. Hiv-1 is the major cause of aids in the usa. It differs from hiv-2 by its molecular structure. Hiv-2 has predominantly been seen in africa and appears less pathogenic than hiv-1, although the differences ultimately have little weight on outcome. An antigen is the chemical structure which stimulates the formation of antibodies, and the difference is a serological one.
Is testing negative several times negative for hiv 1 and hiv 2 after 16 years of unprotected sex is to fear about. Last such test done in June 2015.I?
Tests very reliable. The standard tests for HIV, including those used in India (a medically sophisticated country) are 100% reliable if enough time has passed since the last possible exposure. Depending on exactly which tests you had, your last negative result proves you did not have HIV from any exposure up to 4-8 weeks earlier. It doesn't matter how high the risks for HIV were at the time; the test result rules!
Yes. While it is possible, it is very uncommon and infrequent.
Possible. Since hiv2 is found only in west africa, the probability of a person getting it along with hiv1 would be from having had blood contact with an infected person from that part of the world.
Yes. Infection with either hiv-1 or hiv-2 is not protective against a superimposed infection by the other virus. So in theory, yes, one could get both in one individual. Hiv-2 is fairly uncommon in the us so infection with it is unlikely.
Do HIV 1 and HIV 2 DNA differ form each other? And is there seperated DNA PCR tests for each or one is enough to catch both?
You mean RNA. These are RNA-based retroviruses. The PCR assays for the two strains are distinct.
Hi I had HIV-1 rna pcr @ 5 wks & 5 mths & HIV ag/ab DUO at 1, 2, 4 & 6 mths. Do I need further testing for HIV-2 or am I safe? I'm in metro Detroit.
Safe. If HIV RNA test was negative at more than 3 months after exposure, you are safe.