3 doctors weighed in:

Which is more potent sinemet (carbidopa and levodopa) or the generic of carbidopa/levodopa?

3 doctors weighed in
Dr. Michael Lin
Internal Medicine
2 doctors agree

In brief: Neither

Generic drugs are held to standards where the manufacturer must prove "bioequivalence" to the branded drug.
The molecules must be structurally the same, and the same standard of quality and purity must be met. The pills and the packaging themselves may look different, but the active ingredient is the same. It can be thought of as the difference between clorox bleach and safeway brand bleach.

In brief: Neither

Generic drugs are held to standards where the manufacturer must prove "bioequivalence" to the branded drug.
The molecules must be structurally the same, and the same standard of quality and purity must be met. The pills and the packaging themselves may look different, but the active ingredient is the same. It can be thought of as the difference between clorox bleach and safeway brand bleach.
Dr. Michael Lin
Dr. Michael Lin
Thank
1 comment
Dr. Eric Farbman
I agree with the above. The exception is likely Sinemet CR. The generic form of this medicine is often very ineffective. The immediate release Sinemet and its generic formulation seem to be virtually identical in effect.
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