What does progressive transformation of germinal centers mean - in relation to his axillary lymph node biopsy.

A reaction pattern. Ptgc is a benign pattern of exaggerated response in some enlarged lymph nodes (chronic lymphadenopathy). There is weak association with hodgkin's disease . Although ptgc is not considered a premalignant lesion in this latter case, your doctor may follow you and possibly biopsy/remove any enlarged lymph nodes in the future (if any) for a similar examination.

Related Questions

Breast lump and axillary lymph node biopsy scheduled in 9 days. New lymph nodes in groin and sever pain in breast do I need to have the biopsy sooner?

Progression. Please call both your regular doc and your surgeon with this change. Nodes developing in other areas and the breast lump possibly increasing in size needs to be evaluated in the next few days. Read more...

found out I have a benign calcified axillary lymph node from ultra sound and mammagram. I was wondering if I should do any follow up such as a biopsy?

It depends. Dense calcifications are usually benign. Certain patterns of node calcification can be seen in metastatic breast cancer, thyroid or ovarian cancer. Coarse intranodal calcifications suggest benign fat necrosis or granulomatous disease. If your calcifications are typically benign, you probably don't need any follow up. Talk to your doc about the results. Read more...

What does it mean if my doc wants a lymph node biopsy?

Excision. A lymph node biopsy is usually recommended because a lymph nofe is enlarged. Three general types of biopsies can be done... An fna (fine needle aspiration)... This provides clusters of cells a pathologist will look at to make a diagnosis. The second is an incisional where a portion of the lymph node is taken. The third is excisional where the entire lymph node is taken. Read more...
Many possibilites. Look up "lymphadenopathy" in google. Most causes are benign. www.thepmc.org. Read more...