Any interaction between using the herbs valerian roots and borago and taking antidepressants venlafaxine 37.5 (modified release) and risperidone?

Don't mix meds. Even though i specialize in natural medicine I do not have patients mix natural and pharmaceutical meds unless it is clear that there is no negative interaction. You are talking about two types of mood disorder treatments and i suggest that you do not mix them. One or the other, with guidance from a professional, is best.