Familial adenomatous polyposis - is it transmissible to everyone in the family?

50% If one parent has the condition, approximately 50% of the children will have it. This is an autosomal dominant pattern of heredity.

Related Questions

How is familial adenomatous polyposis inherited?

Autosomal dominant. Enter omim in your browser and go to the database of all inherited diseases. Autosomal dominant means that affected individuals have one normal and one abnormal gene copy, the abnormal one dominating to cause disease. An affected person has a 50% chance to pass on the abnormal gene and fap with each pregnancy. Read more...

How is familial adenomatous polyposis inherited?

Autosomal Dominant. Fap is inherited in an autosomal dominant fashion. This means that if one parent has the gene, and the other parent doesn't, each child has a 50% chance of receiving the gene for fap. The disease causes hundreds of polyps to form in the colon (see the picture), leading to colon cancer. Read more...

Is it bad to have familial adenomatous polyposis at the age of 49?

R/O colon cancer etc. Fap is an autosomal dominant --presented with 100's adenomatous colorectal polyps. In the classic fap- the risk for colorectal cancer is 100% by the time you reach 45Y.O. In adidition, there is also increased risk for duodenal, stomach, thyroid, CNS cancer.Colectomy is recommended to reduce your risk. Upper endoscopy is also recommended. You should see a surgeon re-colectomy-and genetic counsellor. Read more...

What is the definition or description of: familial adenomatous polyposis?

Hereditary condition. Hereditary condition characterized by multiple polyps in colon which are neoplastic and have the potential for malignancy. Read more...

What are chances of my children inheriting the condition familial adenomatous polyposis?

If your family have. If you and some of your family members have it, should undergo genetic counselling and genetic testing. Read more...
Two patterns. Familial adenomatous polyposis can have different inheritance patterns: (1) autosomal dominant (involving apc gene) - one parent has disease, child has 50% chance of getting it; (2) autosomal recessive (mutyh gene) - usually neither parent has disease (both are carriers), child has 25% chance of inheriting the disease. See genetic counselor for help. Read more...

Has anyone heard of fap (familial adenomatous polyposis) outside the amish community?

Yes sure. Fap occurs in approximately 1/10, 000 to 1/30, 000 live births, and accounts for less than 1 % of the total colon cancer risk in the United States it happens not only in amish community- but also in other population- such as in ashkenazi jewish population for instance, etc. Read more...

Can familial adenomatous polyposis affect the whole of the colon?

It can. Also impact on other parts of the GI tract including the duodenum. This inherited disorder also is associated with abdominal desmoid tumors. Read more...

Familial adenomatous polyposis--how often does it progress to cancer?

Nearly always. Adenomatous polyposis coli (apc) nearly always leads to colon cancer. Prophylactic colectomy is recommended for any one with multiple polyps due to apc. Read more...
Polyposis. The risk of colon cancer is eight times higher in patients with familial polyposis than the general population. Read more...