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Please explain why does blood urea nitrogen bun decrease in hepatic failure ?

2 doctors weighed in
Dr. Ed Friedlander
Pathology
1 doctor agrees

In brief: Urea cycle stops

The ammonia that the body generates during metabolism doesn't get detoxified by being turned into urea.

In brief: Urea cycle stops

The ammonia that the body generates during metabolism doesn't get detoxified by being turned into urea.
Dr. Ed Friedlander
Dr. Ed Friedlander
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1 comment
Dr. James Lin
Excellent way to relate the message. I love it. Besides, knowing other reasons is useful, such as malnutrition especially with low protein intake, use of anabolic steroid, pregnancy, etc. Overall, BUN represents the balance between metabolism of protein (extragenous nitrogen) through liver and excretion through kidneys.
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