Please tell me what's the best way to lose weight while you're on duromine?

Don't recommend. Duromine for long term use. To lose weight insure that calories burned > calories consumed. Drink at least 8 - 8 oz glasses of water per day. Try for 8 hours of sleep/night. Aim for at least 5 servings of vegetables & 4 servings of fruit per day. Use whole grain when possible. Avoid sodas, alcohol & junk carbohydrates. Get in a good mix of aerobic & weight lifting exercises.