Can natural anti-inflammatory compounds relieve joint inflammation caused by Lyme disease?

Not really. Lyme disease should be treated with Doxycycline as recommened by the cdc and national academy of medicine, (except in children-amoxicillin, and pregnant females-erythromycin.)you can take an otc NSAID like Aleve (naproxen) for your jont pain, or get an rx from your pcp. Arthritis is a main feature of lyme, and needs more than symptom control. 3-0mega fatty acids can reduce inflammation and improve lipids.