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In what ways can cancer cells escape programmed cell death?

3 doctors weighed in
Dr. Ed Friedlander
Pathology
2 doctors agree

In brief: Mutations

Several of the known mutations that contribute to the malignant phenotype work by opposing the normal mechanisms of apoptosis.
The discovery of bcl2 mutations driving lymphoma was the first of many. Here's a now-classic paper http://carcin.Oxfordjournals.Org/content/21/3/485.Full.

In brief: Mutations

Several of the known mutations that contribute to the malignant phenotype work by opposing the normal mechanisms of apoptosis.
The discovery of bcl2 mutations driving lymphoma was the first of many. Here's a now-classic paper http://carcin.Oxfordjournals.Org/content/21/3/485.Full.
Dr. Ed Friedlander
Dr. Ed Friedlander
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