My doc's been trying diff. Mg's of sugar pills, I'm on glyburide 10mg bid and #'s not getting better. #'s bet. 160-250. Should I just be on insulin?

Depends. It depends on if you're a type 1 or 2 and your a1c. Sometimes you need 2 or more drugs to get things under control. Glyburide is not a good drug. If you need to use a drug in this class, i would use Glimepiride instead. Metformin is the drug of choice for treatment of type 2 dm. Please discuss with your doctor.