2 doctors weighed in:

How long before an average cup of coffee enters your system..What would the caffeines peak time and half life be?

2 doctors weighed in
Dr. Guolin Wen
Pharmacology
1 doctor agrees

In brief: By average 5 hr half

By average the half life of caffeine itself is 5 hours.
It peaks 0.5-2 hours. And it will take 3-4 half lives before it clears out of your body assuming this is a young healthy adult.

In brief: By average 5 hr half

By average the half life of caffeine itself is 5 hours.
It peaks 0.5-2 hours. And it will take 3-4 half lives before it clears out of your body assuming this is a young healthy adult.
Dr. Guolin Wen
Dr. Guolin Wen
Thank
Dr. Eric Levin
Psychiatry

In brief: ? cup of coffee but

For coffee, peak time ; 1/2 life depend upon amount ; binding capacity of active metabolites which vary with brands.
For otc caffeine pills the half life assuming normal liver and kidney functioning is 3-7/hrs. The metabolism is thru the livers cyp450 enzyme system: 1a2 substrate. Information obtained from epocrates online.

In brief: ? cup of coffee but

For coffee, peak time ; 1/2 life depend upon amount ; binding capacity of active metabolites which vary with brands.
For otc caffeine pills the half life assuming normal liver and kidney functioning is 3-7/hrs. The metabolism is thru the livers cyp450 enzyme system: 1a2 substrate. Information obtained from epocrates online.
Dr. Eric Levin
Dr. Eric Levin
Thank
Get help from a real doctor now
Dr. Bennett Machanic
Board Certified, Neurology
48 years in practice
55M people helped
Continue
108,000 doctors available
Read more answers from doctors